Genomic data from the Chinese Rhesus macaque (Macaca mulatta lasiota).

The Chinese rhesus macaque (Macaca mulatta lasiota) is a subspecies of rhesus macaques that mainly resides in western and central China. Due to their anatomical and physiological similarity with human beings, macaques are a common laboratory model. Also, as several macaques species have been sequenced, such as the Indian rhesus macaque and the crab-eating macaque, examination of the Chinese rhesus macaque (CR) genome offers interesting insights into the entire Macaca genus. The DNA sample for data sequencing and analyses was obtained from a five-year old female CR from southwestern China. The genome was sequenced on the IlluminaGAIIx platform, from which 142-Gb of high-quality sequence, representing 47-fold genome coverage for CR. The total size of the assembled CR genome was about 2.84 Gb, providing 47-fold on average. Scaffolds were assigned to the chromosomes according to the synteny displayed with the Indian rhesus macaque and human genome sequences. About 97% of the CR scaffolds could be placed onto chromosomes.

Read the peer-reviewed publication(s):

• Yan, G., Zhang, G., Fang, X., Zhang, Y., Li, C., Ling, F., Cooper, D. N., Li, Q., Li, Y., van Gool, A. J., Du, H., Chen, J., Chen, R., Zhang, P., Huang, Z., Thompson, J. R., Meng, Y., Bai, Y., Wang, J., … Wang, J. (2011). Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Nature Biotechnology, 29(11), 1019–1023. https://doi.org/10.1038/nbt.1992 (PubMed:22002653)

Genome browser:

http://macaque.genomics.org.cn/

Accessions (data included in GigaDB):

GENBANK: AEHK00000000
BioProject: PRJNA51409

Accessions (data not in GigaDB):

SRA: SRP003590

Projects: