Early Stages of Enterovirus Infection
This extract was created in the absence of an abstract.
Excerpt
In contrast to our knowledge of certain phage systems, very little is known of the mechanisms by which most animal viruses attach to and enter host cells, and release their nucleic acid genome from its protective capsid. This paper will briefly review studies carried out by ourselves and others on these early stages in enterovirus infection, and will present new evidence for physical effects on virus resulting from interaction with cell membrane receptors. Much of our earlier work reviewed here was done in collaboration with L. C. McLaren and the late J. T. Syverton.
THE NATURE OF CELL RECEPTORS FOR ENTEROVIRUSES AND THEIR IMPLICATION AS DETERMINANTS OF VIRUS HOST RANGE AND TISSUE TROPISMS
With the establishment of the animal virus plaque technique Dulbecco and his associates (1952) opened up the development of simple methods for quantitating, attachment to animal cells. Bachtold et al. (1957) showed that poliovirus attached to monkey...
