Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Reaction of Triethyloxonium Fluoroborate with Acid Amide. III. Formation of Quinazoline and 4H-3, 1-Benzoxazin-4-one Derivatives
TAKEHIKO KATOATSUSHI TAKADATAKEO UEDA
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1976 Volume 24 Issue 3 Pages 431-436

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Abstract

Reaction of 2-acetaminobenzamide with triethyloxonium fluoroborate gave 2-methyl-3, 4-dihydro-4-quinazolinone. On the other hand, in the reaction of 2-benzoylaminobenzamide in lieu of acetyl derivative with triethyloxonium fluoroborate were obtained 2-phenyl-4H-3, 1-benzoxazin-4-one and 2-phenyl-4-ethoxyquinazoline. And, the reaction of 2-benzoylaminothiobenzamide with triethyloxonium fluoroborate was obtained 4-ethylthio-2-phenylquinazoline.

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© The Pharmaceutical Society of Japan
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