SYNTHESIS OF OPTICALLY ACTIVE TELEOCIDIN DERIVATIVES. ABSOLUTE CONFIGURATION OF TELEOCIDIN B AND OLIVORETIN A

Yasuyuki Endo; Koichi Shudo; Kimio Furuhata; Haruo Ogura; Shinichiro Sakai; Norio Aimi; Yukio Hitotsuyanagi; Yasumasa Koyama

doi:10.1248/cpb.32.358

Yasuyuki Endo, Koichi Shudo, Kimio Furuhata, Haruo Ogura, Shinichiro Sakai, Norio Aimi, Yukio Hitotsuyanagi, Yasumasa Koyama

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Keywords: tumor promoter

JOURNAL FREE ACCESS

1984 Volume 32 Issue 1 Pages 358-361

DOI https://doi.org/10.1248/cpb.32.358

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Abstract

Optically active 3, 4, 5, 6, 7, 8-hexahydro-4 (S)-hydroxymethyl-7 (S)-isopropyl-8-methyl-6-oxo [1, 4] diazonino [7, 6, 5-cd] indole was synthesized from N-Boc-4-nitro-L-tryptophanol and a circular dichroism study of the compound shows that the nine-membered ring of teleocidin B and olivoretin A is S, S configuration.

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