Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
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Six New 2-(2-Phenylethyl)chromones from Agarwood
Tenji KonishiTakao KonoshimaYasuo ShimadaShiu Kiyosawa
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2002 Volume 50 Issue 3 Pages 419-422

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Abstract

Six new chromones, 6-methoxy-2-[2-(3-methoxy-4-hydroxyphenyl)ethyl]chromone (2), 6,8-dihydroxy-2-(2-phenylethyl)chromone (3), 6-hydroxy-2-[2-(4-hydroxyphenyl)ethyl]chromone (4), 6-hydroxy-2-[2-(2-hydroxyphenyl)ethyl]chromone (5), 7-hydroxy-2-(2-phenylethyl)chromone (6), and 6-hydroxy-7-methoxy-2-(2-phenylethyl)chromone (7) were isolated from the ether extract of agarwood in addition to a known compound, 2-(2-phenylethyl)chromone or flidersiachromone (1). Their structures were determined by spectroscopic methods including UV, IR, and NMR spectral data and comparisons with the calculated values using the hydroxyl and methoxyl substituent increments of the chromone ring.

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© 2002 The Pharmaceutical Society of Japan
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