New A-Ring Lactone Triterpenoid Saponins from the Roots of Platycodon grandiflorum

Wen-Wei Fu; Noriko Shimizu; Tadahiro Takeda; De-Qiang Dou; Baohui Chen; Yue-Hu Pei; Ying-Jie Chen

doi:10.1248/cpb.54.1285

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New A-Ring Lactone Triterpenoid Saponins from the Roots of Platycodon grandiflorum

Wen-Wei Fu, Noriko Shimizu, Tadahiro Takeda, De-Qiang Dou, Baohui Chen, Yue-Hu Pei, Ying-Jie Chen

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Keywords: Platycodon grandiflorum, saponin, platycogenic acid A lactone, platycoside M-1, platycoside M-2, platycoside M-3

JOURNAL FREE ACCESS

2006 Volume 54 Issue 9 Pages 1285-1287

DOI https://doi.org/10.1248/cpb.54.1285

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Abstract

Three new A-ring lactone triterpenoid saponins, platycoside M-1 [3-O-β-D-glucopyranosyl platycogenic acid A lactone], platycoside M-2 [3-O-β-D-glucopyranosyl platycogenic acid A lactone 28-O-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranoside], and platycoside M-3 [3-O-β-D-glucopyranosyl platycogenic acid A lactone 28-O-β-D-xylopyranosyl-(1→4)-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranoside], were isolated from the roots of Platycodon grandiflorum A. DC. Their chemical structures were elucidated on the basis of their spectral data and chemical evidence.

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