Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
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Excavatoids L—N, New 12-Hydroxybriaranes from the Cultured Octocoral Briareum excavatum (Briareidae)
Jui-Hsin SuBo-Yuan ChenTsong-Long HwangYung-Husan ChenI-Chu HuangMei-Ru LinJih-Jung ChenLee-Shing FangWei-Hsien WangJan-Jung LiJyh-Horng SheuPing-Jyun Sung
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2010 Volume 58 Issue 5 Pages 662-665

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Abstract

Three new 12-hydroxybriarane diterpenoids, excavatoids L—N (1—3), have been isolated from the cultured octocoral Briareum excavatum. The structures of new briaranes 1—3 were elucidated by the interpretations of spectroscopic methods. Excavatoid L (1) displayed moderate inhibitory effects on superoxide anion generation and elastase release by human neutrophils.

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© 2010 The Pharmaceutical Society of Japan
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