Chlorinated Briarane Diterpenoids from the Sea Whip Gorgonian Corals Junceella fragilis and Ellisella robusta (Ellisellidae)

Su-Hui Wang; Yu-Chia Chang; Michael Y. Chiang; Yung-Husan Chen; Tsong-Long Hwang; Ching-Feng Weng; Ping-Jyun Sung

doi:10.1248/cpb.58.928

Regular Articles

Chlorinated Briarane Diterpenoids from the Sea Whip Gorgonian Corals Junceella fragilis and Ellisella robusta (Ellisellidae)

Su-Hui Wang, Yu-Chia Chang, Michael Y. Chiang, Yung-Husan Chen, Tsong-Long Hwang, Ching-Feng Weng, Ping-Jyun Sung

Author information

Su-Hui Wang
Graduate Institute of Marine Biotechnology, Department of Life Science and Graduate Institute of Biotechnology, National Dong Hwa University
National Museum of Marine Biology and Aquarium
Yu-Chia Chang
Graduate Institute of Marine Biotechnology, Department of Life Science and Graduate Institute of Biotechnology, National Dong Hwa University
National Museum of Marine Biology and Aquarium
Michael Y. Chiang
Department of Chemistry, National Sun Yat-sen University
Yung-Husan Chen
National Museum of Marine Biology and Aquarium
Tsong-Long Hwang
Graduate Institute of Natural Products, Chang Gung University
Ching-Feng Weng
Graduate Institute of Marine Biotechnology, Department of Life Science and Graduate Institute of Biotechnology, National Dong Hwa University
Ping-Jyun Sung
Graduate Institute of Marine Biotechnology, Department of Life Science and Graduate Institute of Biotechnology, National Dong Hwa University
National Museum of Marine Biology and Aquarium
Department of Marine Biotechnology and Resources, Asia-Pacific Ocean Research Center, National Sun Yat-sen University

Keywords: Junceella fragilis, fragilide, Ellisella robusta, robustolide, briarane

JOURNAL FREE ACCESS

2010 Volume 58 Issue 7 Pages 928-933

DOI https://doi.org/10.1248/cpb.58.928

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Abstract

A new chlorinated briarane, fragilide J (1), has been isolated from the sea whip gorgonian coral Junceella fragilis. In addition, the sea whip gorgonian coral Ellisella robusta yielded two chlorinated briaranes, including a new compound, robustolide L (2), and a known metabolite, robustolide H (3). The structures of these compounds were determined using spectroscopic methods. The structure, including the absolute configuration of 3, was further confirmed by X-ray data analysis for the first time.

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