Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
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Speradines F–H, Three New Oxindole Alkaloids from the Marine-Derived Fungus Aspergillus oryzae
Xiao HuQi-Wen XiaYang-Yang ZhaoQiu-Hong ZhengQin-Ying LiuLi Chen Qi-Qing Zhang
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2014 Volume 62 Issue 9 Pages 942-946

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Abstract

A rare hexacyclic oxindole alkaloid, speradine F (1), together with two novel tetracyclic oxindole alkaloids, speradines G (2) and H (3), were isolated from the marine-derived fungus Aspergillus oryzae. Their structures were determined by spectroscopic methods and X-ray diffraction analysis. This study is the first report on cyclopiazonic acid (CPA)-type alkaloids with a hexacyclic skeleton.

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© 2014 The Pharmaceutical Society of Japan
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