1966 Volume 88 Issue 2 Pages 99-102
Urinary excretion of AICA (4-amino-5-imidazolecarboxamide) following an oral dose of AICA was greater in amount in two cases with formiminotransferase deficiency syndrome as compared with those in controls.
A possibility of an impaired incorporation of exogenous AICA into purine biosynthesis in formiminotransferase deficiency syndrome is suggested.