Abstract
Lignins are major class of natural products present in the natural kingdom, and are formed through phenolic oxidative coupling process in the plant. Lignin is a multifunctional natural polymer that has the potential to be developed into a major industrial raw material for multitude of applications. After cellulose and hemicelluloses, lignin is considered to be the most abundant polymer present on planet earth. Many studies have confirmed the potential application of lignins and related compounds in vivo and in vitro. This paper is a review of the most significant results present in the literature concerning the biological and pharmacological applications of lignins and related compounds. The evidence reviewed here will facilitate the identification of what is known in this area, the gaps that exist, and the future research that holds the most potential and promise to affect the human health.
Keywords: Lignins, Pharmacological application, Oxidative stress, Antiviral, Antitumor, Immunomodulatory.
Current Organic Chemistry
Title:Pharmacological Applications of Lignins and Lignins Related Compounds: An Overview
Volume: 16 Issue: 16
Author(s): Verónica Martínez, Montserrat Mitjans and Maria P. Vinardell
Affiliation:
Keywords: Lignins, Pharmacological application, Oxidative stress, Antiviral, Antitumor, Immunomodulatory.
Abstract: Lignins are major class of natural products present in the natural kingdom, and are formed through phenolic oxidative coupling process in the plant. Lignin is a multifunctional natural polymer that has the potential to be developed into a major industrial raw material for multitude of applications. After cellulose and hemicelluloses, lignin is considered to be the most abundant polymer present on planet earth. Many studies have confirmed the potential application of lignins and related compounds in vivo and in vitro. This paper is a review of the most significant results present in the literature concerning the biological and pharmacological applications of lignins and related compounds. The evidence reviewed here will facilitate the identification of what is known in this area, the gaps that exist, and the future research that holds the most potential and promise to affect the human health.
Export Options
About this article
Cite this article as:
Martínez Verónica, Mitjans Montserrat and Vinardell P. Maria, Pharmacological Applications of Lignins and Lignins Related Compounds: An Overview, Current Organic Chemistry 2012; 16 (16) . https://dx.doi.org/10.2174/138527212802651223
DOI https://dx.doi.org/10.2174/138527212802651223 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
Call for Papers in Thematic Issues
Advances of Heterocyclic Chemistry with Pesticide Activity
Global food safety and security will continue to be a global concern for the next 50 years and beyond. Plant diseases have had a significant impact on food safety and security throughout the entire food chain, from primary production to consumption. While conventional chemical pesticides have been traditionally used for ...read more
Calculation design of covalent/metal organic framework based catalysts
This research area combines theoretical computation and screening with machine learning for the design of covalent/metal organic framework-based catalysts, bridging the disciplines of organic chemistry, physical chemistry, computational chemistry, materials science, and machine learning. It covers several critical aspects: designing and synthesizing organic catalysts for improved performance, applying computational methods ...read more
Carbohydrates conversion in biofuels and bioproducts
Biomass pretreatment, hydrolysis, and saccharification of carbohydrates, and sugars bioconversion in biofuels and bioproducts within a biorefinery framework. Carbohydrates derived from woody biomass, agricultural wastes, algae, sewage sludge, or any other lignocellulosic feedstock are included in this issue. Simulation, techno-economic analysis, and life cycle analysis of a biorefinery process are ...read more
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
Related Journals
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Antioxidants in Health, Disease and Aging
CNS & Neurological Disorders - Drug Targets Adipose Tissue Derived Stem Cells for Regeneration and Differentiation into Insulin-Producing Cells
Current Stem Cell Research & Therapy Histone Deacetylase (HDAC) Inhibitors - emerging roles in neuronal memory, learning, synaptic plasticity and neural regeneration
Current Neuropharmacology Circular RNAs and Glioma: Small Molecule with Big Actions
Current Molecular Medicine Is a "Mitochondrial Psychiatry" in the Future? A Review
Current Psychiatry Reviews Role of the APP Non-Amyloidogenic Signaling Pathway and Targeting α-Secretase as an Alternative Drug Target for Treatment of Alzheimers Disease
Current Medicinal Chemistry AFM-Based Single Molecule Techniques: Unraveling the Amyloid Pathogenic Species
Current Pharmaceutical Design Journey Describing the Cytotoxic Potential of Withanolides: A Patent Review
Recent Patents on Anti-Cancer Drug Discovery N-3 (Omega-3) Polyunsaturated Fatty Acids in the Pathophysiology and Treatment of Depression: Pre-Clinical Evidence
CNS & Neurological Disorders - Drug Targets Spectroscopic Characterization of a Pyridine Alkaloid from an Endophytic Strain of the Fusarium incarnatum-equiseti Species Complex
Current Bioactive Compounds Cell Arrest and Apoptosis Induced by the Next Generation of Vanadium Based Drugs: Action Mechanism to Structure Relation and Future Perspectives
Anti-Cancer Agents in Medicinal Chemistry Mediterranean Diet and Dementia of the Alzheimer Type
Current Aging Science Murine Models of Vpr-Mediated Pathogenesis
Current HIV Research Cell Death in Mammalian Development
Current Pharmaceutical Design Voltage Gated ion Channels: Targets for Anticonvulsant Drugs
Current Topics in Medicinal Chemistry Bee Venom: Its Potential Use in Alternative Medicine
Anti-Infective Agents Role of Tumor Microenvironment in Cancer Stem Cells Resistance to Radiotherapy
Current Cancer Drug Targets In silico Analysis of Sulpiride, Synthesis, Characterization and In vitro Studies of its Nanoparticle for the Treatment of Schizophrenia
Current Computer-Aided Drug Design Preferentially Expressed Antigen in Melanoma (PRAME) and the PRAME Family of Leucine-Rich Repeat Proteins
Current Cancer Drug Targets Interaction of Proteins with Lipid Rafts Through Glycolipid-Binding Domains:Biochemical Background and Potential Therapeutic Applications
Current Medicinal Chemistry