Abstract
The use of peptide or peptidomimetic transporters to enable or enhance the uptake of drugs or probe molecules into cells and tissues has received increasing research attention and clinical interest over the past 10 years. This review summarizes a class of transporters that have been studied and focuses on the variation and use of guanidinium based transporters to facilitate the uptake of various types of molecules into cells and tissues. Lead conjugates in this area are currently in clinical trials.
Keywords: Guanidinium, Drug Delivery, Rich Peptide Transporters
Current Protein & Peptide Science
Title: Guanidinium Rich Peptide Transporters and Drug Delivery
Volume: 4 Issue: 2
Author(s): Lee R. Wright, Jonathan B. Rothbard and Paul A. Wender
Affiliation:
Keywords: Guanidinium, Drug Delivery, Rich Peptide Transporters
Abstract: The use of peptide or peptidomimetic transporters to enable or enhance the uptake of drugs or probe molecules into cells and tissues has received increasing research attention and clinical interest over the past 10 years. This review summarizes a class of transporters that have been studied and focuses on the variation and use of guanidinium based transporters to facilitate the uptake of various types of molecules into cells and tissues. Lead conjugates in this area are currently in clinical trials.
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Cite this article as:
Wright R. Lee, Rothbard B. Jonathan and Wender A. Paul, Guanidinium Rich Peptide Transporters and Drug Delivery, Current Protein & Peptide Science 2003; 4 (2) . https://dx.doi.org/10.2174/1389203033487252
DOI https://dx.doi.org/10.2174/1389203033487252 |
Print ISSN 1389-2037 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5550 |
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