Abstract
Pokeweed antiviral protein and several other ribosome inactivating proteins are effective against a broad range of viruses. Recent results have shown that their enzymatic activity is not limited to depurination of the large rRNA, they can depurinate other nucleic acids, including viral RNAs. Antiviral activity of RIPs is summarized here in light of their novel activities and recent developments in the field.
Keywords: antiviral activity, ribosome inactivating proteins, rrna, rips
Mini-Reviews in Medicinal Chemistry
Title: Antiviral Activity Of Ribosome Inactivating Proteins In Medicine
Volume: 4 Issue: 5
Author(s): Bijal A. Parikh and Nilgun E. Tumer
Affiliation:
Keywords: antiviral activity, ribosome inactivating proteins, rrna, rips
Abstract: Pokeweed antiviral protein and several other ribosome inactivating proteins are effective against a broad range of viruses. Recent results have shown that their enzymatic activity is not limited to depurination of the large rRNA, they can depurinate other nucleic acids, including viral RNAs. Antiviral activity of RIPs is summarized here in light of their novel activities and recent developments in the field.
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Cite this article as:
Parikh A. Bijal and Tumer E. Nilgun, Antiviral Activity Of Ribosome Inactivating Proteins In Medicine, Mini-Reviews in Medicinal Chemistry 2004; 4 (5) . https://dx.doi.org/10.2174/1389557043403800
DOI https://dx.doi.org/10.2174/1389557043403800 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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