Abstract
Organic synthesis efficiency can take considerable advantage from microwave heating. Compared to conventional heating, it allows to improve the reactions speed and yield through an energy-efficient, clean, and easy-to-use processing tool. Transition-metal catalyzed cross-coupling reactions and in particular the Suzuki- Miyaura cross-coupling is powerful and widely used tool for the formation of carbon-carbon bonds. Crosscoupling reactions are of large interest for the bonding of a broad range of functional groups, in particular biaryl groups, allowing for a strong stereoselectivity. In this paper, recent research results concerning the application of microwave heating in Suzuki-Miyaura cross-coupling reactions are reviewed with particular emphasis on reactions involving supported Pd as a catalyst.
Keywords: Microwave chemistry, Suzuki-Miyaura reaction, supported palladium, C-C bond formation, organoboron compounds, crosscoupling.
Graphical Abstract
Call for Papers in Thematic Issues
Exploring the Role of Chemical Graph Theory in Advancing Current Organic Synthesis
Organic synthesis is a fundamental discipline in chemistry, crucial for the creation of complex molecules with diverse applications in pharmaceuticals, materials science, and beyond. However, the process of designing efficient synthetic routes for target molecules remains challenging. Chemical graph theory, a branch of theoretical chemistry, offers powerful tools for understanding ...read more
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