The Detection of CMV in Saliva Can Mark a Systemic Infection with CMV in Renal Transplant Recipients
Abstract
:1. Introduction
2. Results
2.1. Frequency of CMV DNA Detection in Saliva and Plasma
2.2. CMV DNA Detected in Saliva is Associated with Immunological Responses to CMV
2.3. CMV DNA Displayed Weak Positive Associations with Cardiovascular Risk
3. Discussion
4. Materials and Methods
4.1. Study Cohort
4.2. Detection of CMV DNA in Plasma and Saliva
4.3. Immunological Assessments of CMV Burden
4.4. Assessment of Vascular Pathology
4.5. Statistical Analyses
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
Abbreviations
AU | Arbitrary units |
cIMT | Carotid intimal media thickness |
CMV | Human cytomegalovirus |
CVD | Cardiovascular disease |
FMD | Flow mediated dilatation |
PBMC | Peripheral blood mononuclear cells |
qPCR | Quantitative PCR |
RTR | Renal transplant recipients |
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Waters, S.; Lee, S.; Lloyd, M.; Irish, A.; Price, P. The Detection of CMV in Saliva Can Mark a Systemic Infection with CMV in Renal Transplant Recipients. Int. J. Mol. Sci. 2019, 20, 5230. https://0-doi-org.brum.beds.ac.uk/10.3390/ijms20205230
Waters S, Lee S, Lloyd M, Irish A, Price P. The Detection of CMV in Saliva Can Mark a Systemic Infection with CMV in Renal Transplant Recipients. International Journal of Molecular Sciences. 2019; 20(20):5230. https://0-doi-org.brum.beds.ac.uk/10.3390/ijms20205230
Chicago/Turabian StyleWaters, Shelley, Silvia Lee, Megan Lloyd, Ashley Irish, and Patricia Price. 2019. "The Detection of CMV in Saliva Can Mark a Systemic Infection with CMV in Renal Transplant Recipients" International Journal of Molecular Sciences 20, no. 20: 5230. https://0-doi-org.brum.beds.ac.uk/10.3390/ijms20205230