Comparison of the Roles of Tea Polysaccharides and Polyphenols in Growth Inhibition of Hepatoma H22 Cells in Mice

Yan Li Fan; Wen Hang Wang; Yuan Shu Hu; Qi Rong; An Guo Teng; An Jun Liu

doi:10.4028/www.scientific.net/AMR.690-693.1193

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HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 690-693Comparison of the Roles of Tea Polysaccharides and...

Comparison of the Roles of Tea Polysaccharides and Polyphenols in Growth Inhibition of Hepatoma H22 Cells in Mice

Abstract:

The effects of tea polysaccharides (TPS) and polyphenols (TPP) on the growth inhibition of hepatoma H22 cells in mice including the roles of them in immune stimulation were investigated. The results showed that TPS and TPP both significantly inhibited the growth of H22 transplantable tumor in mice without statistical difference, both remarkably decreased the spleen index and increased the thymus index compared with that of model group (p<0.05). In addition, TPS and TPP significantly improved the splenocyte proliferation induced by ConA or LPS, and notably enhanced the macrophage phagocytosis towards neutral red. The comparison showed the effect of TPS on immune stimulation was superior to that of TPP to some extent.

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Periodical:

Advanced Materials Research (Volumes 690-693)

Pages:

1193-1197

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.690-693.1193

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Online since:

May 2013

Authors:

Yan Li Fan, Wen Hang Wang, Yuan Shu Hu, Qi Rong, An Guo Teng, An Jun Liu

Keywords:

Anti-Tumor, Macrophage Phagocytosis, Splenocyte Proliferation, Tea Polyphenols, Tea Polysaccharides

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