Flavonoids and Cytotoxic Activity of Gentiana algida Pall

Ai Mei Yang; Xiao Long Shi; Han Han; Yun Men; Rui Wu

doi:10.4028/www.scientific.net/AMR.852.278

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Flavonoids and Cytotoxic Activity of Gentiana algida Pall
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HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 852Flavonoids and Cytotoxic Activity of Gentiana...

Flavonoids and Cytotoxic Activity of Gentiana algida Pall

Abstract:

Four flavonoids were isolated from the EtOAc extract of Gentiana algida Pall. The structures of these compounds were elucidated as: patulitrin (1), Isoscoparin (2), swertisin (3), swertiajaponin (4). These compounds were identified on the basis of comparing their NMR datas with those of corresponding compounds in the literature. The cytotoxic activity of all these compounds were investigated on the growth of HepG-2 cells, the result showed that compound 2 have high cytotoxic activity, the IC₅₀ value is 47.25g/ml.

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Periodical:

Advanced Materials Research (Volume 852)

Pages:

278-281

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.852.278

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Online since:

January 2014

Authors:

Ai Mei Yang, Xiao Long Shi, Han Han, Yun Men, Rui Wu

Keywords:

Cytotoxic Activity, Extraction, Flavonoid, Gentiana algida Pall, Separation

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