Long-Term Study of Osteoconductivity of Bioactive Porous Titanium Metals: Effect of Sodium Removal by Dilute HCl Treatment

Kojiro Tanaka; Mitsuru Takemoto; Shunsuke Fujibayashi; Keiichi Kawanabe; Tomiharu Matsushita; Tadashi Kokubo; Takashi Nakamura

doi:10.4028/www.scientific.net/KEM.396-398.353

Paper Titles

Hydroxyapatite Nucleation on Modified Silicon Surface for Use in Biosensors
p.337

Improvement of Apatite-Forming Ability of Titanium Metal Enriched with Calcium Ion on its Surface
p.341

In Vitro Assessment of Hydroxyapatite and Si-Substituted Hydroxyapatite Coatings under Different VPS Conditions
p.345

Influence of Electrolyte Composition and Time Deposition on TiO₂ Films Produced by Micro-Arc Oxidation
p.349

Long-Term Study of Osteoconductivity of Bioactive Porous Titanium Metals: Effect of Sodium Removal by Dilute HCl Treatment
p.353

Mechanical Properties of Anti-Infectious, Bio-Active and Wear Resistant Ceramic Implant Surface Coatings
p.357

Morphological Study of Apatite Formation on NaOH- and Heat-Treated Titanium Metal
p.361

Nanomechanical Properties of Titanium Coated with Octacalcium Phosphate by Immersion in a Simplified Simulated Body Fluid
p.365

Nanometer Coatings of Hydroxyapatite Characterized by Glancing-Incidence X- Ray Diffraction
p.369

HomeKey Engineering MaterialsKey Engineering Materials Vols. 396-398Long-Term Study of Osteoconductivity of Bioactive...

Long-Term Study of Osteoconductivity of Bioactive Porous Titanium Metals: Effect of Sodium Removal by Dilute HCl Treatment

Abstract:

In a previous study, we have reported that sodium removal by dilute hydrochloric acid (HCl) converted the sodium titanate layer on the surface of an alkali-treated porous titanium into titania with a specific structure that has better bioactivity than sodium titanate. We have shown that a porous titanium with this treatment have good osteoinductivity in soft tissue of canines. In the present study, we investigated the effect of this treatment on the osteoconductive abilities of porous bioactive titanium implant in the long term. Three types of surface treatments were applied: (a) no treatment , (b) alkali, hot water, and heat treatment ( conventional treatment: W-AH treatment), and (c) alkali, dilute HCl, hot water, and heat treatment (Na-free treatment: HCl-AH treatment). We then examined the osteoconductivity of the materials implanted in the femoral condyles of Japanese white rabbits at 6, 12, 26, and 52 weeks. The results showed that the bone ingrowth in HCl-AH porous bioactive titanium was significantly higher than in W-AH porous bioactive titanium at 52 weeks. Therefore, sodium removal has a positive effect on the osteoconductivity of the porous bioactive titanium implant in the long term.

You might also be interested in these eBooks

View Preview

Info:

Periodical:

Key Engineering Materials (Volumes 396-398)

Pages:

353-356

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.396-398.353

Citation:

Cite this paper

Online since:

October 2008

Authors:

Kojiro Tanaka, Mitsuru Takemoto, Shunsuke Fujibayashi, Keiichi Kawanabe, Tomiharu Matsushita, Tadashi Kokubo, Takashi Nakamura

Keywords:

Long Term Study, Osteoconduction, Porous Titanium, Surface Treatment, Titanium Oxide

Export:

RIS, BibTeX

Price:

Permissions:

Request Permissions

References

[1] N. Tamai, A. Myoui, T. Tomita, T. Nakase, J. Tanaka, T. Ochi, H. Yoshikawa: J Biomed Mater Res Vol. 59 (2002), p.110.

DOI: 10.1002/jbm.1222

Google Scholar

[2] RG . Geesink, K. de Groot, CP. Klein: J Bone Joint Surg Br Vol. 70 (1988), p.17.

Google Scholar

[3] M. Jasty, HE. Rubash, GD. Paiement, CR. Bragdon, J. Parr, WH. Harris: Clin Orthop (1992), p.300.

Google Scholar

[4] T. Kokubo, F. Miyaji, HM. Kim, T. Nakamura: J Am Ceram Soc Vol. 79 (1996), p.1127.

Google Scholar

[5] S. Nishiguchi, H. Kato, M. Neo, M. Oka, HM. Kim, T. Kokubo, T. Nakamura: J Biomed Mater Res Vol. 54 (2001), p.198.

Google Scholar

[6] HM. Kim, T. Kokubo, S. Fujibayashi, S. Nishiguchi, T. Nakamura: J Biomed Mater Res Vol. 52 (2000), p.553.

Google Scholar

[7] S. Fujibayashi, M. Neo, HM. Kim, T. Kokubo, T. Nakamura: Biomaterials Vol. 25(2004), p.443.

Google Scholar

[8] M. Takemoto, S. Fujibayashi, M. Neo, J. Suzuki, T. Kokubo, T. Nakamura: Biomaterials Vol. 26(2005), p.6014.

DOI: 10.1016/j.biomaterials.2005.03.019

Google Scholar

[9] M. Takemoto, S. Fujibayashi, M. Neo, J. Suzuki, T. Matsusita, T. Kokubo, T. Nakamura: Biomaterials Vol. 27 (2006), p.2682.

Google Scholar