Recognition and Electrochemical Sensing of 8-Hydroxydeoxyguanosine with Molecularly Imprinted Poly (ethylene-co-vinyl alcohol) Thin Films

Mei Hwa Lee; Tain Chin Tsai; Chun Yueh Huang; Bin Da Liu; Hung Yin Lin

doi:10.4028/www.scientific.net/KEM.495.331

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Recognition and Electrochemical Sensing of 8-Hydroxydeoxyguanosine with Molecularly Imprinted Poly (ethylene-co-vinyl alcohol) Thin Films
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HomeKey Engineering MaterialsKey Engineering Materials Vol. 495Recognition and Electrochemical Sensing of...

Recognition and Electrochemical Sensing of 8-Hydroxydeoxyguanosine with Molecularly Imprinted Poly (ethylene-co-vinyl alcohol) Thin Films

Abstract:

Biosensors using the mechanisms of electrochemical, optical, mass sensitive thermometric and magnetometric have been intensively investigated [1], and molecularly imprinted polymers (MIPs) has been used as recognition elements in sensors reviewed in numerous articles [1-3]. A severe challenge for MIP sensors is detection in chemically diverse environments, such as biological fluids [4-7]. There are many biomarkers discovered in biological fluid, like cerebrospinal fluid (CSF), saliva, serum and urine. Important biomarkers such as creatinine [4], urea, and albumin [8], urine contains non-protein nitrogen metabolites, carbohydrates [9], proteins and amino acids [10]; detection of analytes must be made amid this complex chemical background.

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Periodical:

Key Engineering Materials (Volume 495)

Pages:

331-334

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.495.331

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Online since:

November 2011

Authors:

Mei Hwa Lee, Tain Chin Tsai, Chun Yueh Huang, Bin Da Liu, Hung Yin Lin

Keywords:

8-Hydroxydeoxyguanosine, Molecular Imprinting, Poly(Ethylene-Co-Vinyl Alcohol), Potentiostat Sensors

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