Preparation of Porous Hydroxyapatite Scaffolds for Bone Tissue Engineering

Sang Ho Min; Hyeong Ho Jin; Hoy Yul Park; Ik Min Park; Hong Chae Park; Seog Young Yoon

doi:10.4028/www.scientific.net/MSF.510-511.754

Paper Titles

Effect of Indium on the Microstructures and Mechanical Properties of Dental Gold Alloys
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Rheological Characteristics of Mg-Al Alloys with Ceramic Particles for Meta Foam
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An Amperometric Biosensor Using Prussian Blue Modified Electrode
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Preparation of Activated Carbon Fibers by Chemical Activation Method with Hydroxides
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Preparation of Porous Hydroxyapatite Scaffolds for Bone Tissue Engineering
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Synthesis of Biodegradable β-TCP/PLGA Composites Using Microwave Energy
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Synthesis and Magnetic Properties of Fe/SiO₂ Nanocomposite Powders by the Chemical Vapor Condensation Process
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Fabrication of Nanoscale SiC-Based Ceramic Patterns with Near-Zero Residual Layers by Using Imprinting Technique and Reactive Ion Etching
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Preparation of Silver Metallic Sponge from Macroporous Carbon Template
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Preparation of Porous Hydroxyapatite Scaffolds for Bone Tissue Engineering

Abstract:

Porous hydroxyapatite (HAp) scaffolds were successfully prepared by using the HAp slurry based on the replication of polymer sponge substrate. The effect of HAp content in slurry on the pore morphology and size, and density, porosity, and mechanical strength of porous scaffolds was investigated. The scaffolds with average pore sizes ranging from 200 to 400 µm had an open, relatively uniform, and interconnected porous structure. As the HAp content increased, the porosity of scaffold decreased while the density increased. These phenomena were attributed to the fact that the pores became interconnected with more dense and thicker pore walls with increasing HAp content in slurry. The results suggest that the density, porosity, and compressive strength of the porous HAp scaffold were significantly affected by the content of the HAp powder in the slurry.