Nascent RNA-FISH of X-linked genes in human fibroblast clones

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posted on 2016-12-02, 10:33 authored by Irene CantoneIrene Cantone

Image examples of nascent RNA-FISH for HDAC8, WWC3 and RP11-706O15.1 in human fibroblast clones derived from the same female. The analysis is reported in Genome Biology paper "

Allele-specific analysis of cell fusion-mediated pluripotent reprograming reveals distinct and predictive susceptibilities of human X-linked genes to reactivation" authored by Irene Cantone, Gopuraja Dharmalingam, Yi-Wah Chan, Anne-Celine Kohler, Boris Lenhard, Matthias Merkenschlager and Amanda G Fisher

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EMBO and HFSP

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Keywords

Human X chromosome X chromosome reactivation stochasticity cell fusion reprogramming Epigenetics (incl. Genome Methylation and Epigenomics)

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CC BY 4.0

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