The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
Synthesis and Inhibitory Activities of Isochromophilone Analogues against gp120-CD4 Binding
XUE-LONG SUN, HIROAKI TAKAYANAGI, KEIICHI MATSUZAKI, HARUO TANAKA, KIMIO FURUHATA, SATOSHI OMURA
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1996 Volume 49 Issue 7 Pages 689-692

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Abstract

Several isochromophilone analogues were synthesized from sclerotiorin (1) by Wittig reactions and aldol condensation reaction. The structures of the products were elucidated from MS, elemental analysis, 1H NMR and 13C NMR spectra, and their inhibitory activities against gp!20-CD4 binding were determined.

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The Journal of Antibiotics, Series A

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